新闻搜索 内容 标题    
  您所在的位置: 首页 >移植医学>继续教育 > 正文
既往恶性肿瘤病史的尸体器官供体:OPTN/UNOS的最新资料
  编辑:刘培玲 来源:中华器官移植杂志 时间:2007-08-13 15:46     评论0条

大约2%的死者供体器官移植的供体既往有癌症病史。一项对从2000年到2005年OPTN/UNOS的39455例的死者供体数据分析显示有1069例供者有既往癌症病史,这些供者捐献了2508个移植器官,包括1236个肾脏,891个肝脏,199个心脏和82个其他器官。在供体中最常见的过去肿瘤是非黑素瘤性皮肤癌(n=776),其次是中枢神经系统恶性肿瘤(n=642)和宫颈癌(n=336)。一个患有多形性成胶质细胞瘤的供体把致命的肿瘤传给了三个受者。而一个有32年黑素瘤病史的供者早期传播了致命的肿瘤给了的受者,因此,有黑素瘤病史的供者不该被采用。既往有癌症且曾经有非外伤性脑出血的供者需要引起关注,因为这种出血可能是未被认识的转移性肿瘤导致的结果。

Approximately 2% of deceased donor organ transplants result from donors with a past history of cancer. An analysis of Organ Procurement and Transplantation Network/United Network for Organ Sharing data on 39,455 deceased donors from 2000 to 2005 showed 1069 donors had a PHC, resulting in 2508 transplants, including 1236 kidneys, 891 livers, 199 hearts, 100 lungs, and 82 miscellaneous organs. The most common type of previous cancer in the donor was nonmelanoma skin cancer (n=776) followed by central nervous system malignancies (n=642) and carcinoma of the uterine cervix (n=336). One donor with a glioblastoma multiforme transmitted fatal tumors to three recipients. One donor with a history of melanoma 32 years earlier transmitted a fatal melanoma to a single recipient and, therefore, donors with a history of melanoma should not be used. Donors with a past history of cancer who have a nontraumatic cerebral hemorrhage cause concern because this hemorrhage may be the result of an unrecognized metastatic tumor.

 

[责任编辑:唐雷 ]

    发表评论
  关于尸体器官供体的相关新闻